Sciatic nerve

The major nerve supplying motor and sensory functions to the legs. This is the largest peripheral nerve in the body. This nerve later divides to form the tibial and peroneal nerve. It arises from the L4, L5, and S1-S3 spinal nerves. It emerges from the lumbar spine and sacrum into the gluteal region through the sciatic notch. It is the largest diameter nerve in the body.